Migraine and headache:
Indications for TOPAMAX TABLETS:
Migraine prophylaxis. Not been studied for use in acute treatment of migraines.
May swallow caps whole or sprinkle contents onto soft food (swallow immediately). Give in two equally divided doses. Titrate at 1-week intervals to target dose of 100mg/day. Initially 25mg once daily in the PM, then 25mg twice daily, then 25mg in the AM and 50mg in the PM, then 50mg twice daily. Renal impairment (CrCl <70mL/min): reduce dose by ½. Hemodialysis: may need extra dose.